A two-sided P value of less than 0.05 was considered to indicate statistical significance. The approach that was taken to adjust for possible confounding variables is referred to in the techniques section in the Supplementary Appendix. We tested for proof heterogeneity of the result of random assignment to prompt revascularization among sufferers with normal baseline troponin T concentrations and those with abnormal baseline troponin T concentrations in a model that included a multiplicative conversation term together with the main-effect conditions for revascularization and biomarker category. Sensitivity analyses and the methods for assessing change in troponin T concentrations, plus a landmark analysis involving the 1984 individuals with baseline and 1-year follow-up troponin T values, are defined in the Methods section in the Supplementary Appendix.U.S. Patent # 7 7,659,282 titled Pharmaceutical Compositions Comprising Dextromethorphan and Quinidine for the treating Neurological Disorders was issued on February 9, 2010. The brand new patent will provide AVANIR with patent protection for low-dose quinidine formulations of Zenvia used to take care of pseudobulbar affect .S. Patent was a substantial milestone for the Company and significantly enhances the intellectual home profile of Zenvia which include patent and patents applications that claim methods of treating PBA, chronic pain, as well as other neurologic circumstances.S. Patent was a substantial milestone for the Company and significantly enhances the intellectual home profile of Zenvia which include patents and patent applications that state methods of treating PBA, chronic discomfort, as well as other neurologic conditions.S.