They explain that if archaeologists will get more historic remains with cancer, they could better understand how the disease has changed over time. For now, they don’t know just how the cancer formed, but speculate that it could have had something regarding smoke from wood fires, poor genes, or an infectious disease.. 3,000-year-older skeleton discovered riddled with cancer When archeologist Michaela Binder dug through a tomb of skeletons in Sudan, in northeastern Africa, she found one that looked different. The PhD college student from Durham University in England unearthed bones infested with lesions and holes. Right away, she suspected cancer. ‘Initially, I wasn’t sure if this is really a disease because we’ve a lot of termites in the region, who tend to eat bones or tend to make a lot of small holes in the bones,’ she told CBS Information’ Alphonso Van Marsh.That is an enormous number that defies our best statistical equipment and requires advanced systems biology techniques.’ ‘Prostate cancer is specially challenging since it has such a multitude of clinical presentations, with few shared genetic mutations fairly,’ said Dr. Abate Shen. Thus, to find the essential genes that drive prostate tumor, the CUMC group devised a novel experimental approach in which they used computational approaches to compare the gene regulatory systems that drive prostate tumor in humans with those in a genetically built mouse model of the disease.