The same multivariable logistic-regression models were found in each subgroup stratum. Dichotomous data are presented as numbers and %ages, whereas constant data are expressed as means and standard medians or deviations and interquartile ranges, as appropriate. We report 95 percent self-confidence intervals. P values haven’t been modified for multiple comparisons. Data had been analyzed by using SAS software, version 9.1 . Results Individuals From March 2009 through May 2014, a total of 19,196 individuals were eligible for inclusion. Of the, 16,605 patients met at least one exclusion criterion; the individual or a surrogate decision maker declined consent in 81 instances. Therefore, 2510 patients underwent randomization; 80 were withdrawn after randomization because we were unable to obtain primary final result data, leaving 2430 sufferers in the intention-to-treat evaluation .Compresses: Compressing of hot or cold water pack on your own joints is another way to reduce pain. Daily applying of hot and cool water pack on affected areas can naturally ease pain of joint. 5. Exercise: Exercise regularly is one more natural remedy to relieve discomfort of joint. It can help to improve the flexibility of joints by spiraling bones. This helps to produce excellent results and ease discomfort in joints. 6. Essential olive oil: Olive oil is an effective cheap natural treatment to alleviate discomfort of joint rigidity. Daily massaging with olive oil on affected can strengthens your joins and decreases pain. 7. Lemon: Lemon is certainly among a useful home remedy for pain of joint.