Researchers hypothesized that estradiol might enhance the efficacy profile of rapamycin-coated stents. A total of 500 patients undergoing PCIs in a native coronary vessel were signed up for the ISAR-PEACE research – – Intracoronary Stenting and Angiographic Restenosis: Promote EndotheliAl Cells with Estradiol. All enrolled patients were randomly assigned to get a polymer-free, 17- – estradiolvalerat plus rapamycin-eluting stent or a polymer-free, rapamycin-eluting stent. The stent platform was the ISAR stent with a rough surface, the value of which has been founded by several previous studies.Modern Healthcare: Lawmakers Focus on Geographic Payment Variants Creating a new Medicare payment modifier that increases or decreases hospital reimbursements predicated on their quality and costs would help rein in geographic variants in the program, relating to two Democratic senators. Sens. Al Franken and Sheldon Whitehouse said, Education, Labor and Pensions Committee that they support the creation of a hospital version of the new doctor payment modifier included in the 2010 healthcare overhaul . Bloomberg: Republicans Probe Drugmaker Political Support For Health Law House Republicans are probing whether the White House and Democrats in Congress were promised political support from drugmakers in exchange for limiting what the industry will be asked to contribute under the 2010 health-treatment overhaul, relating to a memo.